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JHEP Reports 2020, 3: 100221

Elevated excretion of p -cresol sulfate was accompanied by a reduced production of N-acetylcysteinyl conjugates of acetaminophen suggesting an impaired ability to detoxify APAP reactive metabolites

Finally, we validated that the peptide inhibitor exhibited robust selectivity for senescent cells and efficiently disrupted FOXO4-p53 foci formation despite its short length and L-type amino acid composition