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Description

In RA patients, HK2 is highly expressed in the synovium, and it inhibits apoptosis and promotes FLS proliferation by acting on mitochondrial channel VDAC (82, 83, 88)

La literatura propone que este efecto se produce a travs de la modulacin de la va 3-adrenrgica y del aumento de AMP cclico intracelular, con incremento de la expresin y actividad de enzimas lipolticas