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Further, although several previous studies have evaluated GSH levels in various extracellular compartments, including bronchoalveolar lavage (BAL) fluid, these studies generally focused on alterations in GSH:GSSG balance in association with disease, or the consumption of GSH during prostaglandin or leukotriene synthesis, with more modest phenotypic, pathophysiologic, or mechanistic information (4, 5)

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251,252 FMD combined with vitamin C can potentially increase the effectiveness of chemotherapy for treating KRAS-mutant cancer cells by reversing the vitamin C-induced upregulation of HO-1 and ferritin