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Practical relevance: Chronic pain is a significant welfare concern in cats, and neuropathic pain, which arises from aberrant processing of sensory signals within the nervous system, is a subcategory of this type of pain

Furthermore, elevated androgen levels can impair hypothalamic sensitivity to progesterone and estradiol, thereby disrupting the inhibitory regulation of GnRH pulsatility

Funding This work was funded by a Rosalind Franklin Fellowship from the University of Groningen to BMB, an NWO grant (Centers for Systems Biology Research) to BMB, DJR and AKG, and an unrestricted research grant from Top Institute for Food and Nutrition to AKG