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1 Introduction Metabolic syndrome (MetS) constitutes a multifaceted array of metabolic disorders, manifesting as disturbances in the bodys handling of energy substrates, including proteins, fats, and carbohydrates

Beyond its pathogenic influence, mtDNA also plays a role in shaping the course of pancreatitis through mechanisms that regulate cell survival, such as balancing apoptosis and necrosis, which are pivotal in determining the severity of the disease (115)