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At the time of the hepatic impairment study, which was conducted after the renal impairment study, the available evidence supported a higher cagrilintide dose of 0.9 mg

Global non-metric multidimensional scaling analysis of experimental variables To evaluate the overall impact of Clc in gluten-fed DQ8-D d -villin-IL-15tg mice, we conducted a global NMDS analysis incorporating a comprehensive set of experimental variables, including gut and plasma auto-Ab levels, plasma cytokines and immunoglobulins, haematological profiles, gliadin concentrations in the stomach and small intestine, body-weight changes, food and water intake, body-mass index and Lee index, faecal humidity and pH, organ weights, morphometric and histological parameters, MLN lymphocyte populations and caecal microbiota composition (Fig