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This suggests that microbial metabolites can directly influence host redox signaling and aging trajectories, potentially linking sleep disturbance-induced dysbiosis to long-term health consequences

What we care about most, though, are interventional studies, where people are randomized to B12 so we can see what happens, and when we look at those, we find there is no increased fracture risk among those given B12

However, because natural live bacteria lack canonical non-homologous end joining machinery, ZFN-induced DSBs frequently trigger bacterial cell death, severely impeding precise, scarless gene editing in prokaryotic hosts [106]