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Importantly, in KK-Ay diabetic mice, antibody-mediated neutralization of elevated IL-17 concentrations improved insulin resistance and increased glucose uptake by skeletal muscle, but not by adipose tissue (146)

At the same time, we must be aware that hypervitaminosis E status may cause abnormal bleeding events by suppressing the synthesis of vitamin K-derived coagulation factors ( Throughout various studies, high doses of vitamin C have generally been observed to be well-tolerated