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When a patient has thrombocytopenia due to B12 deficiency, starting supplements quickly helps restore platelet levels

[8] For these reasons, B12 deficiency is a commonly reported nutritional deficiency following gastric sleeve surgery , with studies and BOMSS guidance indicating that without appropriate supplementation, a significant proportion of patients will develop suboptimal B12 levels within one to two years post-operatively

found no improvements in bone strength or microarchitecture with liraglutide, suggesting that the effects of GLP-1 receptor agonists on bone remodeling may be context-dependent and influenced by metabolic conditions

Phase I Block (Depolarizing Block) Activation of nACh receptors causes membrane depolarization Transient, random muscle fasciculations of varying duration and intensity occur in 94% of patients (Renew, 2026) 5) Continuous membrane depolarization causes inactivation of sodium channels The muscle membrane becomes unresponsive to acetylcholine within 1-2 minutes after i.v