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JMIR Form

GSH and apoptosis Apoptosis is the canonical form of regulated cell death, characterized by cell shrinkage, chromatin condensation, nuclear fragmentation, and the formation of membrane-enclosed apoptotic bodies 31

Future studies should adopt quantitative and standardized methods, such as transmission electron microscopy with immunogold labeling, 221 subcellular fractionation combined with mass spectrometry, 222 and super-resolution imaging in tissue sections, 223 to allow more reliable and comparable evaluation

Overexpression of the exogenous SLC7A11 and SLC3A2 was able to mitigate ferroptosis induced by ER inhibition