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5-Amino-1MQ emerged from medicinal-chemistry programmes screening for selective NNMT inhibitors

( J ) Ferroptosis-related genes were detected by qPCR assay and relative expressions were displayed as a heatmap

Our findings show that both LET7 and HOP1 interact with NLR SUMM2 and regulate its stability, suggesting that SUMM2 could be a client protein of the HSP70/HSP90 chaperone complex