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In HCC, SIRT7 can either synergize with or antagonize SIRT1 pathways, thus influencing key processes like cell proliferation, apoptosis, and therapeutic resistance

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2 (B)) while the repression on l-arginine:glycine amidinotransferase exerted by exogenous creatine permits conservation of the amino acid methionine ( Reference Stead, Au and Jacobs 20 )

Sipos A, Ujlaki G, Mik E et al (2021) The role of the microbiome in ovarian cancer: mechanistic insights into oncobiosis and to bacterial metabolite signaling