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Additionally, they exert neuroprotective effects, safeguarding retinal cells from apoptosis (130, 131), and improve glucose metabolism and insulin sensitivity, both critical for effective glycemic control (132, 133)

This chemical process is implicated in Alzheimers disease, Parkinsons disease, and Huntingtons disease

The prognostic value of elevated plasma TMAO for cardiovascular risk remained significant in various subgroups associated with a reduced overall risk of major cardiovascular events

Second, profound metabolic and oxidative stress from cuproptosis acts as a potent trigger for pathological myocardial reprogramming