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The metabolite GLP-1 (9-36) is neuroprotective and anti-inflammatory in cellular models of neurodegeneration

People with certain allergies Natural spermidine supplements (e.g., Omre) are often derived from wheat germ, which contains a protein that can cause serious adverse effects in people with a gluten or wheat allergy hives, rash, asthma, anaphylaxis.25 Rice germ is another ingredient that you might see in a spermidine supplement, and it too can cause the same adverse effects.26 If you're allergic to either ingredient (or another component used in a particular formulation), you should avoid the product that contains it

A blood biomarker study also found that triglyceride-glucose, C-reactive protein and phosphorus could guide treatment and preventive interventions for metabolic migraine (5)

doi: 10.1016/j.ccell.2019.04.005 40 MostofaADistlerAMeadsMBSahakianEPowersJJAchilleAet al