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EP.342/ can low b12 affect endo related nerve pain and period pain

HNF-3 Is Essential for Node and Notochord Formation in Mouse Development

doi: 10.1038/s41418-019-0380-z 51 KaganVEMaoGQuFAngeliJPDollSCroixCSet al

107 In the presence of oxygen, HIF-1 is hydroxylated, followed by a ubiquitination reaction, leading to the proteolysis of HIF1 through the ubiquitinproteasome system