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[DOI] [PMC free article] [PubMed] [Google Scholar] 413.Karkhaneh R, Faghihi H, Riazi-Esfahani H, Abrishami M, Bazvand F, Ebrahimiadib N, et al

(But) over the last year or two, the studies that have come back really have not shown benefit from doing supplemental vitamin D. Taking too much vitamin D can cause problems such as constipation and nausea and, in more serious cases, kidney stones and kidney damage

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Its an attempt to maximize the growth signals from both systemic and localized pathways