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Description

Traditional low molecular-weight anticancer agents lack tumor selectivity, resulting in wide distribution to healthy tissues and organs and severe systemic toxicity (99)

Francalanci et al., 2023

Electron acceptors are glutathionylated disulfide substrates (GSSR) 1,2,3,10,11,12 or non-glutathione disulfide substrates such as Escherichia coli ribonucleotide reductase (RSSR) 13,14,15 (Fig