Vol. XVIII · Free shipping $75+ · Read the collection
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Description

While cGAS signals via stimulator of interferon genes (STING) to induce predominantly IFN I, TLRs signal via the adaptor protein myeloid differentiation primary response (MyD)88 and the transcription factor NF-B to activate the expression of IL-1, IL-6 and IL-18 and of AIM2, NLRP3 and other elements of the inflammasome

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55,57 These injured or profibrotic tubular cells recruit macrophages, lymphocytes, and fibroblasts, promoting tissue fibrosis and leading to irreversible kidney damage

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A complex glutathione transferase gene family in the houseflyMusca domestica

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doi: 10.1111/j.1600-079X.2011.00856.x 125 ReiterRJTanDXKimSJCruzMH

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