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Major Urinary Protein Urokinase-Type Plasminogen Activator Model A relatively new NASH model has been developed by transiently upregulating ER stress in the liver by delivering major urinary protein urokinase plasminogen activator ( MUP-uPA ) into the hepatocytes via adeno associated virus coupled with a HFD (Nakagawa et al., 2014

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Despite its dry, inflammatory nature, PsO does not spread through contagion