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Fasting depletes Glutathione, turning "safe" Paracetamol doses into a liver toxic emergency. Don't let a therapeutic dose become a lethal one. See the safety protocols on BMJ Best Practice via bio. #MedEd # Biopharmaceutics and Drug Disposition Pharmacology Journal Wiley Online Library acetaminophen depletion of glutathione in various organs The Metabolism and the Synthesis of The mechanisms showing the implication Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential ScienceDirect
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