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COMPARZ Post Hoc Analysis: Characterizing Pazopanib Responders With Advanced Renal Cell Carcinoma

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Studies have explored conjugating ferroptosis inducers, such as RSL3 prodrugs or GPX4-targeting siRNA, to HER2 antibodies or their fragments (e.g., scFv), to construct siRNAantibody fusion nanosystems capable of recognizing and binding to the surface of HER2-positive cells, thereby triggering endocytosis and targeted intracellular drug release