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The biological activity of GHK comes from its ability to bind copper ions (Cu) with high affinity, forming the GHK-Cu complex that has been studied in thousands of published papers

Once the cellular membrane is disrupted by phospholipases, more detrimental chemicals enter the cell, eventually causing the release of apoptotic signals from mitochondria and triggering the caspase-dependent cascade, which leads to the death of cells (Rebai and Amri, 2018