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Whether or not (and how) glutamine-glutamate metabolism of the different isoforms dictates the fate of the metabolites further down the TCA cycle needs further investigation, as well as the potential preferential role of GAC in glutamine dependency over KGA

(2021): Antioxidant-Based Therapies in Male Infertility: Do We Have Sufficient Evidence Supporting Their Effectiveness

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However, due to limitations in methodology and potential bias, the certainty of the evidence is low