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A 2018 paper Targeting Mitochondrial Dysfunction and Oxidative Stress in Activated Microglia using Dendrimer-Based Therapeutics out of Johns Hopkins University Center for Nanomedicine described an improved dendrimer-NAC conjugate called TPP-D-NAC which was able to target the dysfunctional mitochondria found in activated microglial cells and reduce oxidative stress levels substantially as well

(Article in Japanese) Tani M, Sawai Y, Fukuda K, et al

AS causes change in plasma concentrations of LH (Leutinizing Hormone) and FSH (Follicular Stimulating Hormone) by inhibiting hypothalmo-pituitary gonadal axis