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It creeps up, and people often blame stress, lack of sleep, or just getting older. Some of the warning signs include: Feeling wiped out for no reason Numbness or tingling in your hands and feet Pale or washed-out skin Forgetfulness or brain fog Feeling down, irritable, or low in mood Getting dizzy or breathless while doing simple things If these sound familiar, its worth checking your levels before just pushing through

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10.3233/JAD-140681 Summary Keywords vitamin B 12 , cobalamin, homocysteine, methylmalonic acid, holo-transcobalamin, diagnostic algorithm, functional deficiency of B 12 Citation Hannibal L, Lysne V, Bjrke-Monsen A-L, Behringer S, Grnert SC, Spiekerkoetter U, Jacobsen DW and Blom HJ (2016) Biomarkers and Algorithms for the Diagnosis of Vitamin B 12 Deficiency

Pyrolysis of lignin produces a very complex mixture, of which the analysis is very challenging since many of them are not in the EI-MS or MS/MS database