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Once the xenograft tumors for the study of 2DG or BPTES treatment were established (when the tumor volume was ~50100 mm 3 ), the mice were randomly divided into six groups ( n = 5 mice per group) and treated with saline buffer (10% DMSO), 2DG (500 mg/kg/day) or BPTES (12.5 mg/kg/day), each with or without TRAIL (5 g/kg/day), via intraperitoneal injection three times a week for 33 days

DNA Synthesis: Methylcobalamin plays a significant role in DNA synthesis

Therefore, we summarize and respond these public comments in section III.G.7.d of this final rule

Khurana A, Anchi P, Allawadhi P, Kumar V, Sayed N, Packirisamy G, Godugu C