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[54] Ovalocytes are also typically seen on the blood smear, and a pathognomonic feature of megaloblastic anemias (which include PA and others) is hypersegmented neutrophils

Cell-induced thrombin generation in factor XII- and factor IX-deficient plasmas In FXII- and FIX-deficient plasmas, only NB4 and MCF-7 cells retained the capacity to induce thrombin generation (Figure 6A)

These findings implicate MET as a therapeutic target, with strategies like MET agonists or microbiota-based interventions (to modulate gut-brain axis signaling) offering potential benefits