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Irregular meal times or eating during the biological night can desynchronize peripheral clocks from the SCN, contributing to internal misalignment

Some of the most common causes include: Chronic stress and high cortisol Poor or fragmented sleep Hormonal imbalances, including thyroid issues Dehydration Post-viral fatigue, including Long COVID Blood sugar spikes and crashes Nutritional deficiencies, particularly vitamin B12, iron, and vitamin D That last category is where things get interesting

TABLE 1 Lipid Peroxidation (LP) levels, reduced glutathione (GSH) and glutathione peroxidase (GSH-Px) activities in DRG neurons (Control, Se, OX and OX + Se groups) ( a p 0.05 and b p 0.01, etc

RES, resveratrol