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Examples of vectors for expression in Saccharomyces cerevisiae (S.cerevisiae) include pYepSec1(Baldari et al (1987) EMBO J.6: 229

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In some embodiments, the therapeutic agents may be formulated and/or administered with additional active agents such as Vitamin K antagonists, a class of agents that suppress or reduce the action of vitamin K by inhibiting the conversion of oxidized vitamin K (i.e., vitamin K 2,3-epoxide) to its active reduced form (i.e., vitamin K hydroquinone), by inhibiting the enzyme vitamin K epoxide reductase (EC 1.17.4.4

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