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The authors hypothesize that triglyceride accumulation is a hallmark of livers that are more exposed to FFA and hepatic VLDL synthesis is a protective mechanism.30 Alteration in the secretion of adipocytokines from adipocytes contributes to metabolic and inflammatory abnormalities such as alteration in the rate of the synthesis of triglycerides in the hepatocytes and increased lipolysis in central adipose tissue

ROS activate matrix metalloproteinases (MMPs) (Nelson and Melendez, 2004)to degrade extracellular matrix (ECM) (Mori et al., 2019), enabling tumor invasion

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Taking 1 mL working solution as an example, add 100 L DMSO stock solution ( 50.0 mg/mL ) to 400 L PEG300 , and mix evenly