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Qin L, Guitart M, Curull V, Snchez-Font A, Duran X, Tang J, et al

Neuroinflammation 19 , 262 (2022)

N -acetyl transferases create mercapturic acid versions of the xenobiotics which are generally more polar and more water soluble than the parental compound

In addition, the tumor inhibitory effects of sertraline can be further enhanced when combined with compounds causing mitochondrial dysfunction, e.g., rotenone, antimycin A, or the anti-malarial artemether in ser/gly-dependent breast cancer mouse models [34]