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119 In 2011, a groundbreaking study revealed that transcription factor EB (TFEB) broadly regulates genes involved in autophagy and lysosome biogenesis at the transcriptional level, marking a pivotal shift in the understanding of the control of autophagy in the nucleus

Nat Rev Dis Primers (2015) 1:15017

Nervous system function Methylcobalamin is critical for the maintenance of the myelin sheath the protective coating around nerve fibres supporting healthy nerve conduction and normal neurological function.*

Samples for measurements with GSH were also supplemented with 1 U GR and 100 M NADPH to remove traces of GSSG and to maintain a highly reducing redox state