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BMC Gastroenterol 20:242

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These include potential immunogenicity, undefined long-term biosafety profiles of novel nanomaterials, suboptimal drug loading/release kinetics, limited penetration into the invasive tumor margin, and overcoming the immunosuppressive/hypoxic/acidic TME

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KPV inhibits reactive oxygen species production in keratinocytes exposed to oxidative stress[22]

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