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A recent phase II clinical trial in Parkinsons disease, which assessed DFP in 372 newly diagnosed, untreated PD patients over 36 weeks, revealed that DFP not only failed to improve disease symptoms but was associated with a worsening of motor and non-motor symptoms compared to placebo (Devos et al., 2022)

Dose adjustments are necessary for moderate impairment

Remember that peptides are a relatively new area of research and clinical use, and the understanding of their safety and efficacy is continually evolving