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There is no FDA-approved testosterone product for women in the United States, despite strong evidence supporting low-dose testosterone for hypoactive sexual desire, energy, and musculoskeletal health in perimenopausal and postmenopausal women

Cells were washed three times with ice-cold PBS and lysed in lysis buffer (40 mM Tris-HCl (pH 8.0), 1% Triton X-100, 1% NP-40, 10% glycerol, 0.15 M NaCl, 2 mM EDTA, 1 mM phenylmethanesulfonyl fluoride, 1 Complete protease inhibitor cocktail)

These observations are consistent with the hypothesis that NFT activates Nrf2, leading to increased GCL synthesis, and subsequently, to a rise in intracellular glutathione levels