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Description

There were seven patients with LiSA values of 0 dB/m, all of which occurred when CAP values were in the normal range (157 to 258 dB/m) (Figure 1A and 1B)

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A 7-fold increase in bioavailability means that a 500 mcg oral dose of the arginate form could deliver the equivalent systemic exposure of approximately 3,500 mcg of the acetate form taken orally

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Patient selection should prioritize individuals with conditions where established therapies have proven inadequate or are contraindicated

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