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Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury

These results, combined with the observed inhibition of the Toll-like receptor signaling pathway and the NF-B signaling pathway, indicate that the TLR2/4-NF-B signaling pathway plays a crucial role in mediating the alleviation of oxidative stress-induced inflammatory damage by astaxanthin

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