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Mechanically, ADSC-Exos are effectively delivered to the brain through the intranasal administration and is enriched with miR-760-3p to downregulate the expression of CHAC1 and inhibit ferroptosis

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Julian Vyas, Sailesh Kotecha

Mice lacking MLCK210, although may develop GVHD in a Major-Histocompatibility Complex (MHC) mismatched transplant setting, are protected from prolonged intestinal barrier loss and severe GVHD, as shown by reduced tissue damage, decreased number of CD8 + T cells in the gut, and better overall survival [111]