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Slide down until your thighs are as close to parallel with the floor as pain allows

Co-authored by Chris Hasegawa, PhD and Jennifer Mueller, JD This article was co-authored by Chris Hasegawa, PhD and by wikiHow staff writer, Jennifer Mueller, JD

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Chelerythrine inhibits PKC in a concentration-dependent manner by binding to the catalytic ATP or protein-binding site, and not the regulatory region where DAG or phorbol ester bind (Herbert et al., 1990)