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While cuproptosis represents a promising anticancer strategy, its efficacy is limited in solid tumors due to their hypoxic tumor microenvironment (TME) a hallmark feature associated with therapy resistance [39, 206]

This combination couples a long-acting GHRH analog with a selective ghrelin mimic, generating both sustained and acute GH pulses

It is the leading cause of severe vision loss in the elderly Caucasian population in the United States

Furthermore, the mtDNA nt7778 G-to-T polymorphism does not exacerbate cerulein-induced AP in mice but may accelerate the progression of autoimmune-like lesions after tissue damage, particularly in older mice, indicating its potential role for the polymorphism in autoimmune disease susceptibility following pancreatic injury (157)