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At the same time, muscle cells overexpressing MOTS-c can improve glucose uptake, which is mainly related to the activation of AMPK pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Kusminski CM, Bickel PE, Scherer PE

[2] The lower headline number in REDEFINE 2 than in REDEFINE 1 is the expected pattern weight loss is typically smaller in populations with type 2 diabetes and is a good reminder that a trials population matters as much as its drug