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15 Moreover, cancer-associated fibroblasts (CAFs) derived from the stroma of brain metastasis express increased levels of the chemokine ligand CXCL12, thereby enhancing the migration of breast cancer cells, which express its receptor, CXCR4, to the brain (Fig

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b-c , SDS-PAGE gel of His-tagged GPX4 U46C and GPX4 U46C_R152H as stained by Coomasie Blue

This indicates that Wnt7a is not required for correct bundle orientation and suggests that other Wnt members may compensate for Wnt7a or independently mediate the Wnt/PCP pathway in the developing cochlea (Dabdoub et al., Wnt5a , which is expressed in the Kllikers organ medial to the organ of Corti (Qian et al., 2007)