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17 (9), e1009927

Notably, some of these Cl transporters in -cells can be directly targeted by thiazide and loop diuretics (Di Fulvio and Aguilar-Bryan, 2019)

Specific Populations Effect Of Age Neonates Children within the first two months of life have a markedly decreased ability to eliminate valproate compared to older children and adults

Should be measured in every case Draw 4 hours after time of ingestion (levels 4 hours or unknown immediate sAPAP repeat in 4 hours If initial sAPAP undetectable observe individual and repeat sAPAP in 4 hours Time of ingestion and sAPAP are the best predictors of hepatotoxicity Hepatotoxicity Acetaminophen