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Additionally, venous and arterial thrombosis was attenuated, both peripherally and centrally, with reduced brain, heart, lung, liver, kidney, and gastrointestinal lesions, and counteracted acute pancreatitis, as either an initial or final result (severe intracerebral and intraventricular hemorrhage at the time when the pancreas exhibited only edema)

The epsin N-terminal homology (ENTH) domain and the AP180 N-terminal homology (ANTH) domain from epsins and Hip1R proteins form a membrane remodelling complex (AENTH) in the presence of PIP 2 34 enabling the connection between the membrane, the clathrin coat and the actin cytoskeleton 30

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