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Notably, there were significant differences in the relative abundance of Lactobacillus at different taxonomic levels after QCHS treatment (Fig

Choochuay K, Chunhacha P, Pongrakhananon V, Luechapudiporn R, Chanvorachote P

All lines of evidence indicate that fast and slow TGR inhibitors bind different conformational states present in the TGR enzymatic cycle induced by both NADPH-dependent reduction and the concomitant destabilization of the polypeptide chain, as shown by TSA

Bile acids are synthesized from cholesterol and serum levels of 7-hydroxy-4-cholesten-3-one (C4), an intermediate product of this process, reflect the activity of bile acid synthesis (168)