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The Panel notes that if a clinician chooses to administer a "cocktail" preparation, then he or she should be aware that DMSO potentially enhances absorption of other substances, creating the possibility for toxicity from drugs such as lidocaine

As the first step, studies have shown that ototoxic drugs, such as aminoglycoside antibiotics and cisplatin, exit the Blood-Labyrinth Barrier (BLB) into the stria vascularis and subsequently enter the endolymph-filled cochlear duct

Nataf R, Skorupka C, Lam A, Springbett A, Lathe R (2008) Porphyrinuria in childhood autistic disorder is not associated with urinary creatinine deficiency

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