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Product Specifications Test Results Sample: Cagrilinitide, Semaglutide 5/5mg Certificate of Analysis Certificate of Analysis (Endotoxin) Third-party tested for ~99% purity Cagrilintide Properties Source: PubChem Form: Lyophilized powder Unit size: 2.5,5mg/vial Unit quantity: 1 vial Molecular formula: C 194 H 312 N 54 O 59 S 2 Molecular weight: 4409 g/mol Sequence: XKCNTATCATQRLAEFLRHSSNNFGPILPPTNVGSNTP CAS number: 1415456-99-3 Semaglutide Properties Source: PubChem Form: Lyophilized powder Unit size: 2.5/5mg/vial Unit quantity: 1 vial Molecular formula: C 187 H 291 N 45 O 59 Molecular weight: 4114 g/mol Synonym: NN9535 Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc--Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH CAS number: 910463-68-2 Frequently Asked Questions Related Products 3 of 45 products KPV (10mg) PNC-27 (10mg) How It Works Precision Synthesis Synthesized in dedicated, state of-the-art facilities

Although astrocyte reactivity is likely in the first instance to be targeted at maintaining CNS homoeostasis and circuit functions, various mechanisms could alter astrocyte functions in potentially detrimental ways, including (i) persistent reactivity may contribute to chronic neurodegenerative disorders or chronic inflammation, (ii) ageing and cellular senescence which may alter and reduce astrocyte functional capacities, or (iii) genetic mutations in diseased astrocytes or polymorphisms may alter normal astrocyte functions or responses