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The main mechanism of action of Phentermine/Topiramate extended release(ER) is possibly the alteration of various neurotransmitters, including inhibition of voltage-dependent sodium channels, glutamate receptors, and carbonic anhydrase as well as potentiation of -aminobutyrate activity (83).Two large randomized, double-blind, placebo-controlled trials took place (EQUIP and CONQUER) followed by a 2-year extension trial (SEQUEL)

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Recalls & Warnings August 08, 2017 Study Shows Severe Risk in Drinking Hydrogen Peroxide An analysis of records from the National Poison Data System from a 10-year period ending in 2011 identified 294 reported incidents of people developing adverse symptoms after ingesting 35% (high-concentration) hydrogen peroxide (H 2 0 2 )

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