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It is well established that exhaustive exercise increases circulating NH 3 (Reference Weiner and Verlander68) , and one possible explanation for the enhanced glutamine within the brain could be to detoxify the brain via the removal of NH 3 through the synthesis of glutamine using GS (Reference Conway and Hutson69)

Nearly 65, 61, and 58% of CPT were released after 10 h at pH 2.4, 5.5, and 7.0, respectively

Itoh et al., 2018), it is now understood that they also display inherent functional heterogeneity (Liddelow et al., 2017

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