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Therefore, there is an urgent need to identify treatments that are both safer and more efficacious, prompting ongoing research aimed at uncovering drugs that are more potent and less toxic

After incubation, cells were rewashed with PBS and imaged under a fluorescence microscope (Axiovert 40CFL with Axiocam MRm, Zeiss, Germany)

Discussion GPX4, a selenoprotein and an intracellular antioxidant, is the only antioxidative enzyme that can directly reduce phospholipid hydroperoxides generated in biological membranes

Transappendageal pathway The permeation of substances through hair follicles, known as the transfollicular route, or sweat ducts is considered part of the appendageal or shunt route